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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
30.91
Human Site:
S374
Identified Species:
48.57
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S374
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S440
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
L350
F
S
K
V
M
E
P
L
F
R
Q
L
A
K
C
Dog
Lupus familis
XP_538927
602
69962
S374
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
P326
E
F
V
K
I
M
E
P
L
F
R
Q
L
A
K
Rat
Rattus norvegicus
XP_001062510
563
65413
E353
E
E
I
L
D
V
I
E
P
S
E
F
S
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
F256
S
K
V
M
E
P
L
F
R
Q
L
A
K
C
V
Chicken
Gallus gallus
XP_419321
459
53699
G261
Y
E
T
E
H
H
N
G
I
A
E
L
L
E
I
Frog
Xenopus laevis
NP_001087638
506
58853
H308
L
K
V
L
L
P
L
H
K
V
K
S
L
S
V
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
S361
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
S455
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Honey Bee
Apis mellifera
XP_392477
724
84384
S355
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
S349
K
F
W
P
K
V
H
S
P
K
E
V
M
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
K312
L
P
L
K
D
E
H
K
V
F
L
V
R
V
L
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S547
R
Y
W
P
K
I
N
S
T
K
E
I
M
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
0
100
N.A.
6.6
13.3
N.A.
0
6.6
0
100
N.A.
100
100
N.A.
93.3
P-Site Similarity:
100
100
20
100
N.A.
20
26.6
N.A.
20
33.3
20
100
N.A.
100
100
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
14
0
7
7
14
7
7
0
0
67
0
0
7
0
% E
% Phe:
7
54
0
0
0
0
0
7
7
14
0
7
0
54
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
7
54
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
7
7
0
7
0
0
7
0
0
7
% I
% Lys:
47
14
7
14
54
0
0
7
7
54
7
0
7
14
7
% K
% Leu:
14
0
7
14
7
0
14
7
7
0
14
14
20
0
60
% L
% Met:
0
0
0
7
7
7
0
0
0
0
0
0
54
0
0
% M
% Asn:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
54
0
14
7
7
54
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
7
7
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
7
7
7
0
7
0
0
% R
% Ser:
7
7
0
0
0
0
0
54
0
7
0
7
7
7
0
% S
% Thr:
0
0
7
0
0
40
0
0
7
0
0
0
0
0
0
% T
% Val:
0
0
20
7
0
14
0
0
7
7
0
54
0
7
20
% V
% Trp:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _